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651 21st AVE S NAPLES, FL 341021 / 49

$7,950,000

651 21st AVE S

location_onNAPLES, FL 34102 · Collier County

6Beds9Baths7,185Sq Ft2002Built

About This Property

One or more photo(s) has been virtually staged, AI generated or rendered. Tucked away in one of Naples’ most prestigious waterfront neighborhoods, this masterfully designed residence is a sanctuary of elegance, comfort, and mindful living. Set on a prized T-lot with expansive canal views, the home offers exceptional privacy, easy boating access, and the rare ability to accommodate a large vessel with ease. Inside, a refined blend of traditional design and modern luxury creates a warm, welcoming atmosphere. With six spacious bedrooms—each with its own private ensuite—the home effortlessly balances everyday functionality with elevated style. A separate guest suite with its own entrance, kitchenette, and laundry facilities offers exceptional flexibility for visitors or extended family. Soaring ceilings and thoughtfully curated architectural details define the interior, from the grand arched passages to the custom millwork and serene color palette. A dedicated meditation space and the home's northern rear orientation invite harmony and wellbeing, creating a peaceful retreat inspired by principles of balanced design. The home also includes two half-baths, a pool bath, and an elevator for convenience. A handsome study with panoramic water views provides a perfect work-from-home setting, while a temperature-controlled wine room offers the ideal environment to store and showcase a curated collection. Engineered for healthy living, the property is equipped with a state-of-the-art three-tank whole-house reverse osmosis system that delivers high-quality, purified water throughout. Lush landscaping, private terraces, and an outdoor setting reminiscent of a Mediterranean villa make this home feel like a world away—yet it’s just moments from the beach, upscale shopping, and top-tier dining. Whether you're searching for a luxurious year-round home or a remarkable seasonal getaway, this exceptional property offers the perfect combination of location, lifestyle, and long-term value in the heart of coastal Naples.

infoProperty Details

Property Type
Single Family Residence
Year Built
2002
Living Area
7,185 sqft
Lot Size
0.34 acres
Bedrooms
6
Bathrooms
9
Garage Spaces
3
Ownership
Single Family
Days on Market
242
List Date
Jul 24, 2025
Annual Taxes
$71K (2024)
HOA Fee
$0

chairInterior Features

Appliances

DishwasherDisposalDryerMicrowaveRefrigerator/FreezerSelf Cleaning OvenWasherWater Treatment Owned

Flooring

TileWood

Cooling

Ceiling Fan(s)Central Electric

Heating

Central ElectricFireplace(s)

yardExterior & Lot

Construction

Concrete BlockStucco

Roof

Tile

Parking

Attached

Pool

In GroundGas HeatPool BathSee Remarks

Waterfront

No Bridge(s)/Water DirectBayCanal FrontNavigable Water

View

Canal

Listed By

John R Wood Properties

239-261-6622